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Study of Methylene Blue Ototoxicity in the Guinea Pig.

Belhassen S, Alzahrani M, Nader ME, Gaboury L, Saliba I

Division of Otolaryngology-Head and Neck Surgery, University of Montreal, Sainte-Justine University Hospital Center (CHU SJ), Montreal, Quebec, Canada.

Methylene blue is widely used in the medical field, especially as a blue dye for staining. It is also used as a photosensitizing agent in antimicrobial photodynamic therapy, which once photoactivated is effective for the eradication of several multi-resistant bacteria. The objective of this study was to investigate the ototoxic potential of methylene blue and precise its use in otology.

J Clin Med Res 2017;9(11):900-906.

Pubmed ID: 29038666

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