Cytosolic galectin-7 impairs p53 functions and induces chemoresistance in breast cancer cells.
INRS-Institut Armand-Frappier, 531 Blv, des Prairies, Laval, Quebec H7V 1B7, Canada. firstname.lastname@example.org.
Resistance to apoptosis induced by anti-cancer drugs is a major obstacle for the treatment of aggressive forms of breast cancer. Galectin-7 (gal-7) was recently shown to be specifically expressed in basal-like but not in luminal subtypes of human breast cancer.
BMC Cancer 2014;14:801.
Pubmed ID: 25367122