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Early detection of liver steatosis by magnetic resonance imaging in rats infused with glucose and Intralipid solutions and correlation to insulin levels.

d'Assignies G, Fontés G, Kauffmann C, Latour M, Gaboury L, Boulanger Y, Van Beers BE, Soulez G, Poitout V, Tang A

Department of Radiology, University of Montreal, Hôpital Saint-Luc, 1058 rue Saint-Denis, Montreal, Quebec, Canada, H2X 3J4; Research Center CHUM, Hôpital Saint-Luc, 264, René-Lévesque Blvd. East, Montreal, Quebec, Canada, H2X 1P1; Department of Radiology, Beaujon Hospital, Université Paris VII, 100 Bd du Général Leclerc, 92118 Clichy, France.

Magnetic resonance (MR) techniques allow noninvasive fat quantification. We aimed to investigate the accuracy of MR imaging (MRI), MR spectroscopy (MRS) and histological techniques to detect early-onset liver steatosis in three rat phenotypes assigned to an experimental glucolipotoxic model or a control group.

Metab. Clin. Exp. 2013;62(12):1850-7.

Pubmed ID: 24035445

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