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CENP-A: the key player behind centromere identity, propagation, and kinetochore assembly.

De Rop V, Padeganeh A, Maddox PS

Institute for Research in Immunology and Cancer (IRIC), Department of Pathology and Cell Biology, Université de Montréal, C.P. 6128, Succursale Centre-ville, Montréal, Québec H3C 3J7, Canada.

Chromosome segregation is the one of the great problems in biology with complexities spanning from biophysics and polymer dynamics to epigenetics. Here, we summarize the current knowledge and highlight gaps in understanding of the mechanisms controlling epigenetic regulation of chromosome segregation.

Chromosoma 2012;121(6):527-38.

Pubmed ID: 23095988

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