Wound healing: GTPases flux their muscles.
Institute for Research in Immunology and Cancer (IRIC), Université de Montréal, P.O. Box 6128, Station Centre-Ville Montréal QC, H3C 3J7 Canada.
Actomyosin rings are transient organelles that execute cytokinesis, morphogenesis, and wound healing. In this issue of Developmental Cell, Burkel et al. (2012) call into question the assumption that such rings close via sliding filament contractility and elegantly reveal flux of Rho family GTPases within these dynamic structures.
Dev. Cell 2012;23(2):236-8.
Pubmed ID: 22898773