Publications

Les découvertes réalisées à l’IRIC ont permis des avancées majeures à l’égard de la compréhension du développement du cancer et ouvrent la voie à la mise au point de nouvelles solutions thérapeutiques plus ciblées. Ses publications en sont le reflet. Elles rendent également compte du dynamisme et de la productivité des chercheurs de l’Institut.



Structural Maintenance of Chromosome (SMC) Proteins Link Microtubule Stability to Genome Integrity.Laflamme G, Tremblay-Boudreault T, Roy MA, Andersen P, Bonneil E, Atchia K, Thibault P, D'Amours D, Kwok BHJ. Biol. Chem. 2014-10-03;289(40):27418-31.

Break-induced replication requires DNA damage-induced phosphorylation of pif1 and leads to telomere lengthening.Vasianovich Y, Harrington LA, Makovets SPLoS Genet. 2014-10-01;10(10):e1004679.

Dimerization-induced allostery in protein kinase regulation.Lavoie H, Li JJ, Thevakumaran N, Therrien M, Sicheri FTrends Biochem. Sci. 2014-10-01;39(10):475-486.

The chemokine CXC4 and CC2 receptors form homo- and heterooligomers that can engage their signaling G-protein effectors and βarrestin.Armando S, Quoyer J, Lukashova V, Maiga A, Percherancier Y, Heveker N, Pin JP, Prézeau L, Bouvier MFASEB J. 2014-10-01;28(10):4509-23.

Cord blood expansion. Pyrimidoindole derivatives are agonists of human hematopoietic stem cell self-renewal.Fares I, Chagraoui J, Gareau Y, Gingras S, Ruel R, Mayotte N, Csaszar E, Knapp DJ, Miller P, Ngom M, Imren S, Roy DC, Watts KL, Kiem HP, Herrington R, Iscove NN, Humphries RK, Eaves CJ, Cohen S, Marinier A, Zandstra PW, Sauvageau GScience 2014-09-19;345(6203):1509-12.

Expression and functions of galectin-7 in ovarian cancer.Labrie M, Vladoiu MC, Grosset AA, Gaboury L, St-Pierre YOncotarget 2014-09-15;5(17):7705-21.

The Catalytic Activity of the Mitogen-Activated Protein Kinase Extracellular Signal-Regulated Kinase 3 Is Required To Sustain CD4+ CD8+ Thymocyte Survival.Marquis M, Daudelin JF, Boulet S, Sirois J, Crain K, Mathien S, Turgeon B, Rousseau J, Meloche S, Labrecque NMol. Cell. Biol. 2014-09-15;34(18):3374-87.

LKB1 when associated with methylatedERα is a marker of bad prognosis in breast cancer.Bouchekioua-Bouzaghou K, Poulard C, Rambaud J, Lavergne E, Hussein N, Billaud M, Bachelot T, Chabaud S, Mader S, Dayan G, Treilleux I, Corbo L, Le Romancer MInt. J. Cancer 2014-09-15;135(6):1307-18.

Computational identification of RNA functional determinants by three-dimensional quantitative structure-activity relationships.Blanchet MF, St-Onge K, Lisi V, Robitaille J, Hamel S, Major FNucleic Acids Res. 2014-09-08;42(17):11261-71.

Mapping the Putative G Protein-coupled Receptor (GPCR) Docking Site on GPCR Kinase 2: INSIGHTS FROM INTACT CELL PHOSPHORYLATION AND RECRUITMENT ASSAYS.Beautrait A, Michalski KR, Lopez TS, Mannix KM, McDonald DJ, Cutter AR, Medina CB, Hebert AM, Francis CJ, Bouvier M, Tesmer JJ, Sterne-Marr RJ. Biol. Chem. 2014-09-05;289(36):25262-75.

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