Publications

Les découvertes réalisées à l’IRIC ont permis des avancées majeures à l’égard de la compréhension du développement du cancer et ouvrent la voie à la mise au point de nouvelles solutions thérapeutiques plus ciblées. Ses publications en sont le reflet. Elles rendent également compte du dynamisme et de la productivité des chercheurs de l’Institut.



VRQ397 (CRAVKY): a novel noncompetitive V2 receptor antagonist.Rihakova L, Quiniou C, Hamdan FF, Kaul R, Brault S, Hou X, Lahaie I, Sapieha P, Hamel D, Shao Z, Gobeil F, Hardy P, Joyal JS, Nedev H, Duhamel F, Beauregard K, Heveker N, Saragovi HU, Guillon G, Bouvier M, Lubell WD, Chemtob SAm. J. Physiol. Regul. Integr. Comp. Physiol. 2009-10-01;297(4):R1009-18.

Drosophila Larp associates with poly(A)-binding protein and is required for male fertility and syncytial embryo development.Blagden SP, Gatt MK, Archambault V, Lada K, Ichihara K, Lilley KS, Inoue YH, Glover DMDev. Biol. 2009-10-01;334(1):186-97.

Agonist-biased signaling via proteinase activated receptor-2: differential activation of calcium and mitogen-activated protein kinase pathways.Ramachandran R, Mihara K, Mathur M, Rochdi MD, Bouvier M, Defea K, Hollenberg MDMol. Pharmacol. 2009-10-01;76(4):791-801.

Functional selectivity of natural and synthetic prostaglandin EP4 receptor ligands.Leduc M, Breton B, Galés C, Le Gouill C, Bouvier M, Chemtob S, Heveker NJ. Pharmacol. Exp. Ther. 2009-10-01;331(1):297-307.

Implementation of a Canadian external quality assurance program for breast cancer biomarkers: an initiative of Canadian Quality Control in immunohistochemistry (cIQc) and Canadian Association of Pathologists (CAP) National Standards Committee/Immunohistochemistry.Terry J, Torlakovic EE, Garratt J, Miller D, Köbel M, Cooper J, Bahzad S, Pilavdzic D, O'Malley F, O'Brien AE, SenGupta S, Alport E, Têtu B, Knight B, Pettigrew NM, Berendt R, Wolber R, Trotter MJ, Riddell RH, Gaboury L, Elms F, Magliocco A, Barnes P, Gown AM, Gilks CBAppl. Immunohistochem. Mol. Morphol. 2009-10-01;17(5):375-82.

Loss of Erk3 function in mice leads to intrauterine growth restriction, pulmonary immaturity, and neonatal lethality.Klinger S, Turgeon B, Lévesque K, Wood GA, Aagaard-Tillery KM, Meloche SProc. Natl. Acad. Sci. U.S.A. 2009-09-29;106(39):16710-5.

A dimerization-dependent mechanism drives RAF catalytic activation.Rajakulendran T, Sahmi M, Lefrançois M, Sicheri F, Therrien MNature 2009-09-24;461(7263):542-5.

A granulocyte-macrophage colony-stimulating factor and interleukin-15 fusokine induces a regulatory B cell population with immune suppressive properties.Rafei M, Hsieh J, Zehntner S, Li M, Forner K, Birman E, Boivin MN, Young YK, Perreault C, Galipeau JNat. Med. 2009-09-01;15(9):1038-45.

Control of p53 multimerization by Ubc13 is JNK-regulated.Topisirovic I, Gutierrez GJ, Chen M, Appella E, Borden KL, Ronai ZAProc. Natl. Acad. Sci. U.S.A. 2009-08-04;106(31):12676-81.

Enhanced protein detection using a trapping mode on a hybrid quadrupole linear ion trap (Q-Trap).Drogaris P, Le Blanc JC, Fitzgerald JE, Lowndes NF, Verreault A, Thibault PAnal. Chem. 2009-08-01;81(15):6300-9.

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