Publications

Les découvertes réalisées à l’IRIC ont permis des avancées majeures à l’égard de la compréhension du développement du cancer et ouvrent la voie à la mise au point de nouvelles solutions thérapeutiques plus ciblées. Ses publications en sont le reflet. Elles rendent également compte du dynamisme et de la productivité des chercheurs de l’Institut.



Cholesterol-dependent separation of the beta2-adrenergic receptor from its partners determines signaling efficacy: insight into nanoscale organization of signal transduction.Pontier SM, Percherancier Y, Galandrin S, Breit A, Galés C, Bouvier MJ. Biol. Chem. 2008-09-05;283(36):24659-72.

The IKK-related kinases: from innate immunity to oncogenesis.Clément JF, Meloche S, Servant MJCell Res. 2008-09-01;18(9):889-99.

Fungal Rtt109 histone acetyltransferase is an unexpected structural homolog of metazoan p300/CBP.Tang Y, Holbert MA, Wurtele H, Meeth K, Rocha W, Gharib M, Jiang E, Thibault P, Verreault A, Cole PA, Marmorstein RNat. Struct. Mol. Biol. 2008-09-01;15(9):998.

A new mechanism controlling kinetochore-microtubule interactions revealed by comparison of two dynein-targeting components: SPDL-1 and the Rod/Zwilch/Zw10 complex.Gassmann R, Essex A, Hu JS, Maddox PS, Motegi F, Sugimoto A, O'Rourke SM, Bowerman B, McLeod I, Yates JR, Oegema K, Cheeseman IM, Desai AGenes Dev. 2008-09-01;22(17):2385-99.

Comprehensive profiling of histone modifications using a label-free approach and its applications in determining structure-function relationships.Drogaris P, Wurtele H, Masumoto H, Verreault A, Thibault PAnal. Chem. 2008-09-01;80(17):6698-707.

Graft-versus-host disease causes failure of donor hematopoiesis and lymphopoiesis in interferon-gamma receptor-deficient hosts.Delisle JS, Gaboury L, Bélanger MP, Tassé E, Yagita H, Perreault CBlood 2008-09-01;112(5):2111-9.

Regional variation of microtubule flux reveals microtubule organization in the metaphase meiotic spindle.Yang G, Cameron LA, Maddox PS, Salmon ED, Danuser GJ. Cell Biol. 2008-08-25;182(4):631-9.

PU.1 expression is modulated by the balance of functional sense and antisense RNAs regulated by a shared cis-regulatory element.Ebralidze AK, Guibal FC, Steidl U, Zhang P, Lee S, Bartholdy B, Jorda MA, Petkova V, Rosenbauer F, Huang G, Dayaram T, Klupp J, O'Brien KB, Will B, Hoogenkamp M, Borden KL, Bonifer C, Tenen DGGenes Dev. 2008-08-01;22(15):2085-92.

Histone H3 K56 hyperacetylation perturbs replisomes and causes DNA damage.Celic I, Verreault A, Boeke JDGenetics 2008-08-01;179(4):1769-84.

Acetylation of histone H3 lysine 56 regulates replication-coupled nucleosome assembly.Li Q, Zhou H, Wurtele H, Davies B, Horazdovsky B, Verreault A, Zhang ZCell 2008-07-25;134(2):244-55.

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