Les découvertes réalisées à l’IRIC ont permis des avancées majeures à l’égard de la compréhension du développement du cancer et ouvrent la voie à la mise au point de nouvelles solutions thérapeutiques plus ciblées. Ses publications en sont le reflet. Elles rendent également compte du dynamisme et de la productivité des chercheurs de l’Institut.

High incidence of invasive aspergillosis associated with intestinal graft-versus-host disease following nonmyeloablative transplantation.Labbé AC, Su SH, Laverdière M, Pépin J, Patiño C, Cohen S, Kiss T, Lachance S, Sauvageau G, Busque L, Roy DC, Roy JBiol. Blood Marrow Transplant. 2007-10-01;13(10):1192-200.

T regulatory cells control numbers of NK cells and CD8alpha+ immature dendritic cells in the lymph node paracortex.Giroux M, Yurchenko E, St-Pierre J, Piccirillo CA, Perreault CJ. Immunol. 2007-10-01;179(7):4492-502.

A comparative analysis of the triloops in all high-resolution RNA structures reveals sequence structure relationships.Lisi V, Major FRNA 2007-09-01;13(9):1537-45.

Ranking the factors that contribute to protein beta-sheet folding.Parisien M, Major FProteins 2007-09-01;68(4):824-9.

Genetic inhibition of cardiac ERK1/2 promotes stress-induced apoptosis and heart failure but has no effect on hypertrophy in vivo.Purcell NH, Wilkins BJ, York A, Saba-El-Leil MK, Meloche S, Robbins J, Molkentin JDProc. Natl. Acad. Sci. U.S.A. 2007-08-28;104(35):14074-9.

Updated recommendations from the Canadian National Consensus Meeting on HER2/neu testing in breast cancer.Hanna W, O'malley FP, Barnes P, Berendt R, Gaboury L, Magliocco A, Pettigrew N, Robertson S, Sengupta S, Têtu B, Thomson TCurr Oncol 2007-08-01;14(4):149-53.

FGF stimulation of the Erk1/2 signalling cascade triggers transition of pluripotent embryonic stem cells from self-renewal to lineage commitment.Kunath T, Saba-El-Leil MK, Almousailleakh M, Wray J, Meloche S, Smith ADevelopment 2007-08-01;134(16):2895-902.

The evasive nature of drug efficacy: implications for drug discovery.Galandrin S, Oligny-Longpré G, Bouvier MTrends Pharmacol. Sci. 2007-08-01;28(8):423-30.

Resonance energy transfer approaches in molecular pharmacology and beyond.Marullo S, Bouvier MTrends Pharmacol. Sci. 2007-08-01;28(8):362-5.

Atypical mitogen-activated protein kinases: structure, regulation and functions.Coulombe P, Meloche SBiochim. Biophys. Acta 2007-08-01;1773(8):1376-87.

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