Publications
Les découvertes réalisées à l’IRIC ont permis des avancées majeures à l’égard de la compréhension du développement du cancer et ouvrent la voie à la mise au point de nouvelles solutions thérapeutiques plus ciblées. Ses publications en sont le reflet. Elles rendent également compte du dynamisme et de la productivité des chercheurs de l’Institut.
An NS3 protease inhibitor with antiviral effects in humans infected with hepatitis C virus.Nature 2003-11-13;426(6963):186-9.
In vitro expansion of hematopoietic stem cells by recombinant TAT-HOXB4 protein.Nat. Med. 2003-11-01;9(11):1428-32.
Nuclear export of ERK3 by a CRM1-dependent mechanism regulates its inhibitory action on cell cycle progression.J. Biol. Chem. 2003-10-24;278(43):42615-24.
Phosphorylation of the MAPKKK regulator Ste50p in Saccharomyces cerevisiae: a casein kinase I phosphorylation site is required for proper mating function.Eukaryotic Cell 2003-10-01;2(5):949-61.
Bimodal regulation of RAF by CNK in Drosophila.EMBO J. 2003-10-01;22(19):5068-78.
An essential function of the mitogen-activated protein kinase Erk2 in mouse trophoblast development.EMBO Rep. 2003-10-01;4(10):964-8.
Unsuspected role of the brain morphogenetic gene Otx1 in hematopoiesis.Proc. Natl. Acad. Sci. U.S.A. 2003-09-02;100(18):10299-303.
Polycomb group genes as epigenetic regulators of normal and leukemic hemopoiesis.Exp. Hematol. 2003-07-01;31(7):567-85.
Rapid turnover of extracellular signal-regulated kinase 3 by the ubiquitin-proteasome pathway defines a novel paradigm of mitogen-activated protein kinase regulation during cellular differentiation.Mol. Cell. Biol. 2003-07-01;23(13):4542-58.
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