Publications

Stereospecific lasofoxifene derivatives reveal the interplay between estrogen receptor alpha stability and antagonistic activity in ESR1 mutant breast cancer cells.Hosfield DJ, Weber S, Li NS, Suavage M, Joiner CF, Hancock GR, Sullivan EA, Nduwke E, Han R, Cush S, Lainé M, Mader SC, Greene GL, Fanning SWElife 2022-05-16;11;e72512.

Dual-function antiandrogen/HDACi hybrids based on enzalutamide and entinostat.Barrett RRG, Nash C, Diennet M, Cotnoir-White D, Doyle C, Mader S, Thomson AA, Gleason JLBioorg Med Chem Lett 2021-11-09;55:128441.

Positive Regulation of Estrogen Receptor Alpha in Breast Tumorigenesis.Porras L, Ismail H, Mader SCells 2021-10-31;10(11).

Minireview: what is known about SUMOylation among NR4A family members?Dodat F, Mader S, Lévesque DJ Mol Biol 2021-08-23:167212.

From Micro to Long: Non-Coding RNAs in Tamoxifen Resistance of Breast Cancer Cells.Barazetti JF, Jucoski TS, Carvalho TM, Veiga RN, Kohler AF, Baig J, Al Bizri H, Gradia DF, Mader S, Carvalho de Oliveira JCancers (Basel) 2021-07-22;13(15).

Complex regulation of orphan nuclear receptor Nur77 (Nr4a1) transcriptional activity by SUMO2 and PIASγ.Dodat F, Cotnoir-White D, Dianati E, Vallet A, Mader S, Lévesque DBiochim Biophys Acta Mol Cell Res 2020-11-13;1868(2):118908.

Cholesterol as an Endogenous Ligand of ERRα Promotes ERRα-Mediated Cellular Proliferation and Metabolic Target Gene Expression in Breast Cancer Cells.Ghanbari F, Mader S, Philip ACells 2020-07-23;9(8).

Isolation and functional characterization of a novel endogenous inverse agonist of estrogen related receptors (ERRs) from human pregnancy urine.Ghanbari F, Hebert-Losier A, Barry J, Poirier D, Giguere V, Mader S, Philip AJ. Steroid Biochem. Mol. Biol. 2019-04-05;191:105352.

Role of SUMOylation in differential ERα transcriptional repression by tamoxifen and fulvestrant in breast cancer cells.Traboulsi T, El Ezzy M, Dumeaux V, Audemard E, Mader SOncogene 2019-02-01;38(7):1019-1037.

Incorporation of histone deacetylase inhibitory activity into the core of tamoxifen - A new hybrid design paradigm.Palermo AF, Diennet M, El Ezzy M, Williams BM, Cotnoir-White D, Mader S, Gleason JLBioorg. Med. Chem. 2018-08-15;26(15):4428-4440.

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