Publications

Starvation-induced proteasome assemblies in the nucleus link amino acid supply to apoptosis.Uriarte M, Sen Nkwe N, Tremblay R, Ahmed O, Messmer C, Mashtalir N, Barbour H, Masclef L, Voide M, Viallard C, Daou S, Abdelhadi D, Ronato D, Paydar M, Darracq A, Boulay K, Desjardins-Lecavalier N, Sapieha P, Masson JY, Sergeev M, Kwok BH, Hulea L, Mallette FA, Milot E, Larrivée B, Wurtele H, Affar EBNat Commun 2021-11-30;12(1):6984.

Structural basis of mechano-chemical coupling by the mitotic kinesin KIF14.Benoit MPMH, Asenjo AB, Paydar M, Dhakal S, Kwok BH, Sosa HNat Commun 2021-06-15;12(1):3637.

BMP signaling is essential for sustaining proximo-distal progression in regenerating axolotl limbs.Vincent E, Villiard E, Sader F, Dhakal S, Kwok BH, Roy SDevelopment 2020-07-31;147(14).

Conditional switching of KIF2A mutation provides new insights into cortical malformation pathogeny.Gilet JG, Ivanova EL, Trofimova D, Rudolf G, Meziane H, Broix L, Drouot N, Courraud J, Skory V, Voulleminot P, Osipenko M, Bahi-Buisson N, Yalcin B, Birling MC, Hinckelmann MV, Kwok BH, Allingham JS, Chelly JHum. Mol. Genet. 2020-03-31;29(5):766-784.

Kinesin Kif2C in regulation of DNA double strand break dynamics and repair.Zhu S, Paydar M, Wang F, Li Y, Wang L, Barrette B, Bessho T, Kwok BH, Peng AElife 2020-01-21;9.

Structural studies of the eIF4E-VPg complex reveal a direct competition for capped RNA: Implications for translation.Coutinho de Oliveira L, Volpon L, Rahardjo AK, Osborne MJ, Culjkovic-Kraljacic B, Trahan C, Oeffinger M, Kwok BH, Borden KLBProc. Natl. Acad. Sci. U.S.A. 2019-12-07;116(48):24056-24065.

Loss-of-function mutations in KIF14 cause severe microcephaly and kidney development defects in humans and zebrafish.Reilly ML, Stokman MF, Magry V, Jeanpierre C, Alves M, Paydar M, Hellinga J, Delous M, Pouly D, Failler M, Martinovic J, Loeuillet L, Leroy B, Tantau J, Roume J, Gregory-Evans CY, Shan X, Filges I, Allingham JS, Kwok BH, Saunier S, Giles RH, Benmerah AHum. Mol. Genet. 2019-03-01;28(5):778-795.

Ternary complex of Kif2A-bound tandem tubulin heterodimers represents a kinesin-13-mediated microtubule depolymerization reaction intermediate.Trofimova D, Paydar M, Zara A, Talje L, Kwok BH, Allingham JSNat Commun 2018-07-06;9(1):2628.

Multimodal and Polymorphic Interactions between Anillin and Actin: Their Implications for Cytokinesis.Jananji S, Risi C, Lindamulage IK, Picard LP, Van Sciver R, Laflamme G, Albaghjati A, Hickson GR, Kwok BH, Galkin VEJ. Mol. Biol. 2017-03-10;429(5):715-731.

High-throughput screening in niche-based assay identifies compounds to target preleukemic stem cells.Gerby B, Veiga DF, Krosl J, Nourreddine S, Ouellette J, Haman A, Lavoie G, Fares I, Tremblay M, Litalien V, Ottoni E, Kosic M, Geoffrion D, Ryan J, Maddox PS, Chagraoui J, Marinier A, Hébert J, Sauvageau G, Kwok BH, Roux PP, Hoang TJ. Clin. Invest. 2016-12-01;126(12):4569-4584.

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