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LRCH proteins: a novel family of cytoskeletal regulators.

Foussard H, Ferrer P, Valenti P, Polesello C, Carreno S, Payre F

Université de Toulouse UPS, Centre de Biologie du Développement, Toulouse, France.

Comparative genomics has revealed an unexpected level of conservation for gene products across the evolution of animal species. However, the molecular function of only a few proteins has been investigated experimentally, and the role of many animal proteins still remains unknown. Here we report the characterization of a novel family of evolutionary conserved proteins, which display specific features of cytoskeletal scaffolding proteins, referred to as LRCHs.

PLoS ONE 2010;5(8):e12257.

Pubmed ID: 20805893

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