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Understanding the words of chromatin regulation.

Wu JI, Lessard J, Crabtree GR

Howard Hughes Medical Institute, Departments of Pathology and Developmental Biology, Stanford University, Stanford, CA 94062, USA.

Recent studies indicate that chromatin regulatory complexes produce biological specificity in the way that letters produce meanings by combinations into words. Combinatorial assembly of chromatin regulatory complexes may be critical for maximizing the information content provided by arrays of histone modifications.

Cell 2009;136(2):200-6.

Pubmed ID: 19167321

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