Esperanto for histones: CENP-A, not CenH3, is the centromeric histone H3 variant.
Wellcome Trust Centre for Cell Biology, University of Edinburgh, Mayfield Road, Edinburgh, EH9 3JR, Scotland, UK, firstname.lastname@example.org.
The first centromeric protein identified in any species was CENP-A, a divergent member of the histone H3 family that was recognised by autoantibodies from patients with scleroderma-spectrum disease. It has recently been suggested to rename this protein CenH3. Here, we argue that the original name should be maintained both because it is the basis of a long established nomenclature for centromere proteins and because it avoids confusion due to the presence of canonical histone H3 at centromeres.
Chromosome Res. 2013;21(2):101-6.
Pubmed ID: 23580138