Publications
IRIC discoveries have spurred major advances in understanding the development of cancer and opened the way to the creation of new, more targeted therapeutic solutions. Its publications are a reflection of these accomplishments. They also demonstrate the Institute’s drive and productivity.
Prediction of Synergism from Chemical-Genetic Interactions by Machine Learning.Cell Syst 2015-12-23;1(6):383-95.
The 20S proteasome core, active within apoptotic exosome-like vesicles, induces autoantibody production and accelerates rejection.Sci Transl Med 2015-12-16;7(318):318ra200.
Design, synthesis and evaluation of antiestrogen and histone deacetylase inhibitor molecular hybrids.Bioorg. Med. Chem. 2015-12-15;23(24):7597-606.
DAF-18/PTEN locally antagonizes insulin signalling to couple germline stem cell proliferation to oocyte needs in C. elegans.Development 2015-12-15;142(24):4230-41.
The experimental power of FR900359 to study Gq-regulated biological processes.Nat Commun 2015-12-14;6:10156.
The lighthouse at the end of the chromosome.F1000Res 2015-12-11;4.
An Antifungal Combination Matrix Identifies a Rich Pool of Adjuvant Molecules that Enhance Drug Activity against Diverse Fungal Pathogens.Cell Rep 2015-11-17;13(7):1481-92.
Association of Treatment with Carvedilol, Bisoprolol and Metoprolol on the Risk of Mortality and Hospital Admission Among Older Adults with Heart Failure.Value Health 2015-11-01;18(7):A379.
Enhancement of mass spectrometry performance for proteomic analyses using high-field asymmetric waveform ion mobility spectrometry (FAIMS).J Mass Spectrom 2015-11-01;50(11):1181-95.
Discovery of protein acetylation patterns by deconvolution of peptide isomer mass spectra.Nat Commun 2015-10-15;6:8648.
The Estrogen Receptor Cofactor SPEN Functions as a Tumor Suppressor and Candidate Biomarker of Drug Responsiveness in Hormone-Dependent Breast Cancers.Cancer Res. 2015-10-15;75(20):4351-63.
Cell cycle timing regulation during asynchronous divisions of the early C. elegans embryo.Exp. Cell Res. 2015-10-01;337(2):243-8.
β-Blockers have differential effects on the murine asthma phenotype.Br. J. Pharmacol. 2015-10-01;172(20):4833-46.
Selective ligand activity at Nur/retinoid X receptor complexes revealed by dimer-specific bioluminescence resonance energy transfer-based sensors.FASEB J. 2015-10-01;29(10):4256-67.
Disclosure of incidental findings in cancer genomic research: investigators' perceptions on obligations and barriers.Clin. Genet. 2015-10-01;88(4):320-6.
Understanding the Polo Kinase machine.Oncogene 2015-09-10;34(37):4799-807.
Trapping cells in senescence with a lamin cage.Cell Cycle 2015-09-02;14(17):2725-6.
The transcriptomic landscape and directed chemical interrogation of MLL-rearranged acute myeloid leukemias.Nat. Genet. 2015-09-01;47(9):1030-7.
Stromal-Derived Factor-1α and Interleukin-7 Treatment Improves Homeostatic Proliferation of Naïve CD4(+) T Cells after Allogeneic Stem Cell Transplantation.Biol. Blood Marrow Transplant. 2015-09-01;21(9):1621-1632.
The NMR structure of the II-III-VI three-way junction from the Neurospora VS ribozyme reveals a critical tertiary interaction and provides new insights into the global ribozyme structure.RNA 2015-09-01;21(9):1621-32.
A Perspective on Studying G-Protein-Coupled Receptor Signaling with Resonance Energy Transfer Biosensors in Living Organisms.Mol. Pharmacol. 2015-09-01;88(3):589-95.
Receptor sequestration in response to β-arrestin-2 phosphorylation by ERK1/2 governs steady-state levels of GPCR cell-surface expression.Proc. Natl. Acad. Sci. U.S.A. 2015-08-31.
Multiple Export Mechanisms for mRNAs.Cells 2015-08-28;4(3):452-73.
β-Arrestin Recruitment and Biased Agonism at Free Fatty Acid Receptor 1.J. Biol. Chem. 2015-08-21;290(34):21131-40.
MiRBooking simulates the stoichiometric mode of action of microRNAs.Nucleic Acids Res. 2015-08-18;43(14):6730-8.
Functional Redundancy of ERK1 and ERK2 MAP Kinases during Development.Cell Rep 2015-08-11;12(6):913-21.
Sex hormones have pervasive effects on thymic epithelial cells.Sci Rep 2015-08-07;5:12895.
Frequency adaptation for enhanced radiation force amplitude in dynamic elastography.IEEE Trans Ultrason Ferroelectr Freq Control 2015-08-01;62(8):1453-66.
Differential Features of AIRE-Induced and AIRE-Independent Promiscuous Gene Expression in Thymic Epithelial Cells.J. Immunol. 2015-07-15;195(2):498-506.
A Mutation in the Carbohydrate Recognition Domain Drives a Phenotypic Switch in the Role of Galectin-7 in Prostate Cancer.PLoS ONE 2015-07-13;10(7):e0131307.
Sample Collection Method Bias Effects in Quantitative Phosphoproteomics.J. Proteome Res. 2015-07-02;14(7):2998-3004.
Comparative analyses of downstream signal transduction targets modulated after activation of the AT1 receptor by two β-arrestin-biased agonists.Front Pharmacol 2015-07-01;6:131.
Small molecule regulation of normal and leukemic stem cells.Curr. Opin. Hematol. 2015-07-01;22(4):309-16.
Whole genome and transcriptome analysis of a novel AML cell line with a normal karyotype.Leuk. Res. 2015-07-01;39(7):709-18.
Translational control by oncogenic signaling pathways.Biochim. Biophys. Acta 2015-07-01;1849(7):753-765.
Caenorhabditis elegans is a useful model for anthelmintic discovery.Nat Commun 2015-06-25;6:7485.
The double capsules in macro-textured breast implants.Biomaterials 2015-06-23;67:65-72.
Undetectable Histone O-GlcNAcylation in Mammalian Cells.Epigenetics 2015-06-15:0.
Phosphoproteome dynamics of Saccharomyces cerevisiae under heat shock and cold stress.Mol. Syst. Biol. 2015-06-03;11(6):813.
RNA-Puzzles Round II: assessment of RNA structure prediction programs applied to three large RNA structures.RNA 2015-06-01;21(6):1066-84.
The Added Value of Statistical Modeling of Backscatter Properties in the Management of Breast Lesions at US.Radiology 2015-06-01;275(3):666-74.
The Smc5-Smc6 heterodimer associates with DNA through several independent binding domains.Sci Rep 2015-05-18;5:9797.
Molecular Pathways: GLI1-Induced Drug Glucuronidation in Resistant Cancer Cells.Clin. Cancer Res. 2015-05-15;21(10):2207-10.
Investigating the regulation of stem and progenitor cell mitotic progression by in situ imaging.Curr. Biol. 2015-05-04;25(9):1123-34.
The Perlecan Fragment LG3 Regulates Homing of Mesenchymal Stem Cells and Neointima Formation During Vascular Rejection.Am. J. Transplant. 2015-05-01;15(5):1205-18.
Interplay between histone h3 lysine 56 deacetylation and chromatin modifiers in response to DNA damage.Genetics 2015-05-01;200(1):185-205.
The atypical MAPK ERK3 controls positive selection of thymocytes.Immunology 2015-05-01;145(1):161-9.
Regulation of RAF protein kinases in ERK signalling.Nat. Rev. Mol. Cell Biol. 2015-04-23;16(5):281-98.
E4F1 Is a Master Regulator of CHK1-Mediated Functions.Cell Rep 2015-04-15;11(2):210-219.
Proteome dynamics in health and disease.J Proteomics 2015-04-06;118:1.
A primary role for kinin B1 receptor in inflammation, organ damage, and lethal thrombosis in a rat model of septic shock in diabetes.Eur J Inflamm 2015-04-01;13(1):40-52.
Effect of the transient pharmacological inhibition of mapk3/1 pathway on ovulation in mice.PLoS ONE 2015-03-24;10(3):e0119387.
[The 2010 years].Med Sci (Paris) 2015-03-01;31 Spec No 1:91-111.
[The 2000 years].Med Sci (Paris) 2015-03-01;31 Spec No 1:47-90.
The expanding role of mTOR in cancer cell growth and proliferation.Mutagenesis 2015-03-01;30(2):169-176.
Defective repair of uracil causes telomere defects in mouse hematopoietic cells.J. Biol. Chem. 2015-02-27;290(9):5502-11.
Sonic Hedgehog factor Gli1: As good as resistant.Mol Cell Oncol 2015-02-24;2(1):e961827.
A Cell-Signaling Network Temporally Resolves Specific versus Promiscuous Phosphorylation.Cell Rep 2015-02-24;10(7):1202-14.
Haploinsufficiency screen highlights two distinct groups of ribosomal protein genes essential for embryonic stem cell fate.Proc. Natl. Acad. Sci. U.S.A. 2015-02-17;112(7):2127-32.
A high-sensitivity phospho-switch triggered by Cdk1 governs chromosome morphogenesis during cell division.Genes Dev. 2015-02-15;29(4):426-39.
Panspecies small-molecule disruptors of heterochromatin-mediated transcriptional gene silencing.Mol. Cell. Biol. 2015-02-15;35(4):662-74.
CDK-1 and Two B-Type Cyclins Promote PAR-6 Stabilization during Polarization of the Early C. elegans Embryo.PLoS ONE 2015-02-06;10(2):e0117656.
Regulation of global and specific mRNA translation by the mTOR signaling pathway.Translation (Austin) 2015-02-02;3(1):e983402.
Noncoding regions of C. elegans mRNA undergo selective adenosine to inosine deamination and contain a small number of editing sites per transcript.RNA Biol 2015-02-01;12(2):162-74.
Syncytium biogenesis: It's all about maintaining good connections.Worm 2015-01-28;4(1):e992665.
The BioGRID interaction database: 2015 update.Nucleic Acids Res. 2015-01-28;43(Database issue):D470-8.
Sentinel Node Biopsy After Neoadjuvant Chemotherapy in Biopsy-Proven Node-Positive Breast Cancer: The SN FNAC Study.J. Clin. Oncol. 2015-01-20;33(3):258-64.
CDC28 phosphorylates Cac1p and regulates the association of chromatin assembly factor i with chromatin.Cell Cycle 2015-01-02;14(1):74-85.
In Vitro and In Vivo Characterization of the Rab11-GAP Activity of Drosophila Evi5.Methods Mol. Biol. 2015-01-01;1298:187-94.
The eukaryotic translation initiation factor eIF4E in the nucleus: taking the road less traveled.Immunol. Rev. 2015-01-01;263(1):210-23.
Crystal structure of a BRAF kinase domain monomer explains basis for allosteric regulation.Nat. Struct. Mol. Biol. 2015-01-01;22(1):37-43.
A phase I trial of ribavirin and low-dose cytarabine for the treatment of relapsed and refractory acute myeloid leukemia with elevated eIF4E.Haematologica 2015-01-01;100(1):e7-9.
EVI1-rearranged acute myeloid leukemias are characterized by distinct molecular alterations.Blood 2015-01-01;125(1):140-3.
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