IRIC discoveries have spurred major advances in understanding the development of cancer and opened the way to the creation of new, more targeted therapeutic solutions. Its publications are a reflection of these accomplishments. They also demonstrate the Institute’s drive and productivity.

Cancer: A drug-resistant duo.Lavoie H, Therrien MNature 2011-12-15;480(7377):329-30.

DNA-binding properties of Smc6, a core component of the Smc5-6 DNA repair complex.Roy MA, D'Amours DBiochem. Biophys. Res. Commun. 2011-12-09;416(1-2):80-5.

A prospective pilot study investigating the musculoskeletal pain in postmenopausal breast cancer patients receiving aromatase inhibitor therapy.Robidoux A, Rich E, Bureau NJ, Mader S, Laperrière D, Bail M, Tremblay N, Patenaude M, Turgeon JCurr Oncol 2011-12-01;18(6):285-94.

PIF1 disruption or NBS1 hypomorphism does not affect chromosome healing or fusion resulting from double-strand breaks near telomeres in murine embryonic stem cells.Reynolds GE, Gao Q, Miller D, Snow BE, Harrington LA, Murnane JPDNA Repair (Amst.) 2011-11-10;10(11):1164-73.

Wnt4 regulates thymic cellularity through the expansion of thymic epithelial cells and early thymic progenitors.Heinonen KM, Vanegas JR, Brochu S, Shan J, Vainio SJ, Perreault CBlood 2011-11-10;118(19):5163-73.

Structural messenger RNA contains cytokeratin polymerization and depolymerization signals.Kloc M, Dallaire P, Reunov A, Major FCell Tissue Res. 2011-11-01;346(2):209-22.

HCaRG accelerates tubular repair after ischemic kidney injury.Matsuda H, Lavoie JL, Gaboury L, Hamet P, Tremblay JJ. Am. Soc. Nephrol. 2011-11-01;22(11):2077-89.

Y-box-binding protein 1 interacts with hepatitis C virus NS3/4A and influences the equilibrium between viral RNA replication and infectious particle production.Chatel-Chaix L, Melançon P, Racine MÈ, Baril M, Lamarre DJ. Virol. 2011-11-01;85(21):11022-37.

Incidence and prognostic value of eosinophilia in chronic graft-versus-host disease after nonmyeloablative hematopoietic cell transplantation.Ahmad I, Labbé AC, Chagnon M, Busque L, Cohen S, Kiss T, Lachance S, Roy DC, Sauvageau G, Roy JBiol. Blood Marrow Transplant. 2011-11-01;17(11):1673-8.

C-terminal domain of MEIS1 converts PKNOX1 (PREP1) into a HOXA9-collaborating oncoprotein.Bisaillon R, Wilhelm BT, Krosl J, Sauvageau GBlood 2011-10-27;118(17):4682-9.

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