IRIC discoveries have spurred major advances in understanding the development of cancer and opened the way to the creation of new, more targeted therapeutic solutions. Its publications are a reflection of these accomplishments. They also demonstrate the Institute’s drive and productivity.

Protein stability and transcription factor complex assembly determined by the SCL-LMO2 interaction.Lécuyer E, Larivière S, Sincennes MC, Haman A, Lahlil R, Todorova M, Tremblay M, Wilkes BC, Hoang TJ. Biol. Chem. 2007-11-16;282(46):33649-58.

[New talk between receptor and trimeric G proteins: "an intertwined body dance"].Galés C, Bouvier MMed Sci (Paris) 2007-11-01;23(11):1031-4.

Isomer-specific retinoic acid biosynthesis in HeLa cells expressing recombinant class I aldehyde dehydrogenases.Brodeur H, Parisotto M, Chagnon S, Mader S, Bhat PVBiochim. Biophys. Acta 2007-11-01;1770(11):1548-56.

Genome-wide expression and location analyses of the Candida albicans Tac1p regulon.Liu TT, Znaidi S, Barker KS, Xu L, Homayouni R, Saidane S, Morschhäuser J, Nantel A, Raymond M, Rogers PDEukaryotic Cell 2007-11-01;6(11):2122-38.

Kinetic characterization and identification of the acylation and glycosylation sites of recombinant human gamma-glutamyltranspeptidase.Castonguay R, Halim D, Morin M, Furtos A, Lherbet C, Bonneil E, Thibault P, Keillor JWBiochemistry 2007-10-30;46(43):12253-62.

Functional calcitonin gene-related peptide receptors are formed by the asymmetric assembly of a calcitonin receptor-like receptor homo-oligomer and a monomer of receptor activity-modifying protein-1.Héroux M, Hogue M, Lemieux S, Bouvier MJ. Biol. Chem. 2007-10-26;282(43):31610-20.

Quantification of dynamic protein complexes using Renilla luciferase fragment complementation applied to protein kinase A activities in vivo.Stefan E, Aquin S, Berger N, Landry CR, Nyfeler B, Bouvier M, Michnick SWProc. Natl. Acad. Sci. U.S.A. 2007-10-23;104(43):16916-21.

Heterotrimeric G protein signaling functions with dynein to promote spindle positioning in C. elegans.Couwenbergs C, Labbé JC, Goulding M, Marty T, Bowerman B, Gotta MJ. Cell Biol. 2007-10-08;179(1):15-22.

Unraveling G protein-coupled receptor endocytosis pathways using real-time monitoring of agonist-promoted interaction between beta-arrestins and AP-2.Hamdan FF, Rochdi MD, Breton B, Fessart D, Michaud DE, Charest PG, Laporte SA, Bouvier MJ. Biol. Chem. 2007-10-05;282(40):29089-100.

The zinc cluster transcription factor Tac1p regulates PDR16 expression in Candida albicans.Znaidi S, De Deken X, Weber S, Rigby T, Nantel A, Raymond MMol. Microbiol. 2007-10-01;66(2):440-52.

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