IRIC discoveries have spurred major advances in understanding the development of cancer and opened the way to the creation of new, more targeted therapeutic solutions. Its publications are a reflection of these accomplishments. They also demonstrate the Institute’s drive and productivity.
Cross-talk between SUMOylation and ISGylation in response to interferon.Cytokine 2020-02-17;129:155025.
Quantitative SUMO proteomics identifies PIAS1 substrates involved in cell migration and motility.Nat Commun 2020-02-14;11(1):834.
Proteogenomics uncovers a vast repertoire of shared tumor-specific antigens in ovarian cancer.Cancer Immunol Res 2020-02-12.
Qualitative Changes in Cortical Thymic Epithelial Cells Drive Postpartum Thymic Regeneration.Front Immunol 2020-02-11;10:3118.
Beta-arrestins operate an on/off control switch for focal adhesion kinase activity.Cell. Mol. Life Sci. 2020-02-10.
Hematopoietic stem cell transplantation using single UM171-expanded cord blood: a single-arm, phase 1-2 safety and feasibility study.Lancet Haematol 2020-01-31;7(2):e134-e145.
F-Actin Interactome Reveals Vimentin as a Key Regulator of Actin Organization and Cell Mechanics in Mitosis.Dev. Cell 2020-01-29;52(2):210-222.e7.
Kinesin Kif2C in regulation of DNA double strand break dynamics and repair.Elife 2020-01-21;9.
The Genomic Landscape of Antigenic Targets for T Cell-Based Leukemia Immunotherapy.Front Immunol 2020-01-13;10:2934.
Conditional switching of KIF2A mutation provides new insights into cortical malformations pathogeny.Hum. Mol. Genet. 2020-01-10.