Publications

Development of a high-throughput assay to identify inhibitors of the ubiquitin-conjugating enzyme UBCH10.Cléroux P, Voisin L, Meloche SSLAS Discov 2022-06-01;27(4):266-271.

YES, a novel therapeutic target in hepatocellular carcinoma.Lapouge M, Meloche SMol Cell Oncol 2022-05-01;9(1):2069993.

ERK3-MK5 signaling regulates myogenic differentiation and muscle regeneration by promoting FoxO3 degradation.Soulez M, Tanguay PL, Dô F, Dort J, Crist C, Kotlyarov A, Gaestel M, Ferron M, Dumont NA, Meloche SJ Cell Physiol 2022-04-01;237(4):2271-2287.

Signaling by the tyrosine kinase Yes promotes liver cancer development.Guégan JP, Lapouge M, Voisin L, Saba-El-Leil MK, Tanguay PL, Lévesque K, Brégeon J, Mes-Masson AM, Lamarre D, Haibe-Kains B, Trinh VQ, Soucy G, Bilodeau M, Meloche SSci Signal 2022-01-18;15(717):eabj4743.

Regulation of Mitogen-Activated Protein Kinase Signaling Pathways by the Ubiquitin-Proteasome System and Its Pharmacological Potential.Mathien S, Tesnière C, Meloche SPharmacol Rev 2021-10-01;73(4):263-296.

Interleukin-17 Receptor D in Physiology, Inflammation and Cancer.Girondel C, Meloche SFront Oncol 2021-03-23;11:656004.

Loss of interleukin-17 receptor D promotes chronic inflammation-associated tumorigenesis.Girondel C, Lévesque K, Langlois MJ, Pasquin S, Saba-El-Leil MK, Rivard N, Friesel R, Servant MJ, Gauchat JF, Lesage S, Meloche SOncogene 2021-01-01;40(2):452-464.

Copper bioavailability is a KRAS-specific vulnerability in colorectal cancer.Aubert L, Nandagopal N, Steinhart Z, Lavoie G, Nourreddine S, Berman J, Saba-El-Leil MK, Papadopoli D, Lin S, Hart T, Macleod G, Topisirovic I, Gaboury L, Fahrni CJ, Schramek D, Meloche S, Angers S, Roux PPNat Commun 2020-07-24;11(1):3701.

Reevaluation of the Role of Extracellular Signal-Regulated Kinase 3 in Perinatal Survival and Postnatal Growth Using New Genetically Engineered Mouse Models.Soulez M, Saba-El-Leil MK, Turgeon B, Mathien S, Coulombe P, Klinger S, Rousseau J, Lévesque K, Meloche SMol. Cell. Biol. 2019-03-15;39(6).

A simple approach for multi-targeted shRNA-mediated inducible knockdowns using Sleeping Beauty vectors.Fink S, Zugelder L, Roth B, Brandt E, Meloche S, Izsvák Z, Bargou RC, Stühmer TPLoS ONE 2018-10-19;13(10):e0205585.

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