Publications

Apelin protects against abdominal aortic aneurysm and the therapeutic role of neutral endopeptidase resistant apelin analogs.Wang W, Shen M, Fischer C, Basu R, Hazra S, Couvineau P, Paul M, Wang F, Toth S, Mix DS, Poglitsch M, Gerard NP, Bouvier M, Vederas JC, Penninger JM, Kassiri Z, Oudit GYProc. Natl. Acad. Sci. U.S.A. 2019-06-25;116(26):13006-13015.

Hybridization of β-Adrenergic Agonists and Antagonists Confers G Protein Bias.Stanek M, Picard LP, Schmidt MF, Kaindl JM, Hübner H, Bouvier M, Weikert D, Gmeiner PJ. Med. Chem. 2019-05-23;62(10):5111-5131.

Chemogenetics defines receptor-mediated functions of short chain free fatty acids.Bolognini D, Barki N, Butcher AJ, Hudson BD, Sergeev E, Molloy C, Moss CE, Bradley SJ, Le Gouill C, Bouvier M, Tobin AB, Milligan GNat. Chem. Biol. 2019-05-01;15(5):489-498.

Bioluminescence resonance energy transfer-based imaging of protein-protein interactions in living cells.Kobayashi H, Picard LP, Schönegge AM, Bouvier MNat Protoc 2019-04-01;14(4):1084-1107.

Biased Signaling of the Mu Opioid Receptor Revealed in Native Neurons.Ehrlich AT, Semache M, Gross F, Da Fonte DF, Runtz L, Colley C, Mezni A, Le Gouill C, Lukasheva V, Hogue M, Darcq E, Bouvier M, Kieffer BLiScience 2019-03-15;14:47-57.

FZD5 is a Gαq-coupled receptor that exhibits the functional hallmarks of prototypical GPCRs.Wright SC, Cañizal MCA, Benkel T, Simon K, Le Gouill C, Matricon P, Namkung Y, Lukasheva V, König GM, Laporte SA, Carlsson J, Kostenis E, Bouvier M, Schulte G, Hoffmann CSci Signal 2018-12-04;11(559).

Functional selectivity profiling of the angiotensin II type 1 receptor using pathway-wide BRET signaling sensors.Namkung Y, LeGouill C, Kumar S, Cao Y, Teixeira LB, Lukasheva V, Giubilaro J, Simões SC, Longpré JM, Devost D, Hébert TE, Piñeyro G, Leduc R, Costa-Neto CM, Bouvier M, Laporte SASci Signal 2018-12-04;11(559).

Structural insights into binding specificity, efficacy and bias of a β2AR partial agonist.Masureel M, Zou Y, Picard LP, van der Westhuizen E, Mahoney JP, Rodrigues JPGLM, Mildorf TJ, Dror RO, Shaw DE, Bouvier M, Pardon E, Steyaert J, Sunahara RK, Weis WI, Zhang C, Kobilka BKNat. Chem. Biol. 2018-11-01;14(11):1059-1066.

Spatiotemporal regulation of the GPCR activity of BAI3 by C1qL4 and Stabilin-2 controls myoblast fusion.Hamoud N, Tran V, Aimi T, Kakegawa W, Lahaie S, Thibault MP, Pelletier A, Wong GW, Kim IS, Kania A, Yuzaki M, Bouvier M, Côté JFNat Commun 2018-10-26;9(1):4470.

Translating biased signaling in the ghrelin receptor system into differential in vivo functions.Mende F, Hundahl C, Plouffe B, Skov LJ, Sivertsen B, Madsen AN, Lückmann M, Diep TA, Offermanns S, Frimurer TM, Bouvier M, Holst BProc. Natl. Acad. Sci. U.S.A. 2018-10-23;115(43):E10255-E10264.

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