Publications

Beta-arrestins operate an on/off control switch for focal adhesion kinase activity.Alexander RA, Lot I, Saha K, Abadie G, Lambert M, Decosta E, Kobayashi H, Beautrait A, Borrull A, Asnacios A, Bouvier M, Scott MGH, Marullo S, Enslen HCell. Mol. Life Sci. 2020-02-10.

Preservation of Post-Infarction Cardiac Structure and Function via Long-Term Oral Formyl Peptide Receptor Agonist Treatment.García RA, Ito BR, Lupisella JA, Carson NA, Hsu MY, Fernando G, Heroux M, Bouvier M, Dierks E, Kick EK, Gordon DA, Chen J, Mintier G, Carrier M, St-Onge S, Shah H, Towne J, Bucardo MS, Ma X, Ryan CS, Wurtz NR, Ostrowski J, Villarreal FJJACC Basic Transl Sci 2020-01-09;4(8):905-920.

Exploring use of unsupervised clustering to associate signaling profiles of GPCR ligands to clinical response.Benredjem B, Gallion J, Pelletier D, Dallaire P, Charbonneau J, Cawkill D, Nagi K, Gosink M, Lukasheva V, Jenkinson S, Ren Y, Somps C, Murat B, Van Der Westhuizen E, Le Gouill C, Lichtarge O, Schmidt A, Bouvier M, Pineyro GNat Commun 2019-09-09;10(1):4075.

Discovery of Potent Protease-Activated Receptor 4 Antagonists with in Vivo Antithrombotic Efficacy.Miller MM, Banville J, Friends TJ, Gagnon M, Hangeland JJ, Lavallée JF, Martel A, O'Grady H, Rémillard R, Ruediger E, Tremblay F, Posy SL, Allegretto NJ, Guarino VR, Harden DG, Harper TW, Hartl K, Josephs J, Malmstrom S, Watson C, Yang Y, Zhang G, Wong P, Yang J, Bouvier M, Seiffert DA, Wexler RR, Lawrence RM, Priestley ES, Marinier AJ. Med. Chem. 2019-08-22;62(16):7400-7416.

Biased agonism of clinically approved μ-opioid receptor agonists and TRV130 is not controlled by binding and signaling kinetics.Pedersen MF, Wróbel TM, Märcher-Rørsted E, Pedersen DS, Møller TC, Gabriele F, Pedersen H, Matosiuk D, Foster SR, Bouvier M, Bräuner-Osborne HNeuropharmacology 2019-07-24:107718.

Agonist-induced desensitisation of β -adrenoceptors: Where, when, and how?Okeke K, Angers S, Bouvier M, Michel MCBr. J. Pharmacol. 2019-07-01;176(14):2539-2558.

Apelin protects against abdominal aortic aneurysm and the therapeutic role of neutral endopeptidase resistant apelin analogs.Wang W, Shen M, Fischer C, Basu R, Hazra S, Couvineau P, Paul M, Wang F, Toth S, Mix DS, Poglitsch M, Gerard NP, Bouvier M, Vederas JC, Penninger JM, Kassiri Z, Oudit GYProc. Natl. Acad. Sci. U.S.A. 2019-06-25;116(26):13006-13015.

Hybridization of β-Adrenergic Agonists and Antagonists Confers G Protein Bias.Stanek M, Picard LP, Schmidt MF, Kaindl JM, Hübner H, Bouvier M, Weikert D, Gmeiner PJ. Med. Chem. 2019-05-23;62(10):5111-5131.

Chemogenetics defines receptor-mediated functions of short chain free fatty acids.Bolognini D, Barki N, Butcher AJ, Hudson BD, Sergeev E, Molloy C, Moss CE, Bradley SJ, Le Gouill C, Bouvier M, Tobin AB, Milligan GNat. Chem. Biol. 2019-05-01;15(5):489-498.

Bioluminescence resonance energy transfer-based imaging of protein-protein interactions in living cells.Kobayashi H, Picard LP, Schönegge AM, Bouvier MNat Protoc 2019-04-01;14(4):1084-1107.

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