Publications
Functional diversity in the RAS subfamily of small GTPases.Biochem Soc Trans 2022-04-29;50(2):921-933.
NMR Detection Methods for Profiling RAS Nucleotide Cycling.Methods Mol Biol 2021-05-12;2262:169-182.
RAS GTPase signalling to alternative effector pathways.Biochem Soc Trans 2020-10-30;48(5):2241-2252.
RASSF effectors couple diverse RAS subfamily GTPases to the Hippo pathway.Sci Signal 2020-10-13;13(653).
Structure of the DOCK2-ELMO1 complex provides insights into regulation of the auto-inhibited state.Nat Commun 2020-07-10;11(1):3464.
SPIN90 associates with mDia1 and the Arp2/3 complex to regulate cortical actin organization.Nat. Cell Biol. 2020-07-01;22(7):803-814.
Conformational resolution of nucleotide cycling and effector interactions for multiple small GTPases determined in parallel.J. Biol. Chem. 2019-06-21;294(25):9937-9948.
Evolution of AF6-RAS association and its implications in mixed-lineage leukemia.Nat Commun 2017-10-23;8(1):1099.
Inhibition of RAS function through targeting an allosteric regulatory site.Nat. Chem. Biol. 2017-01-01;13(1):62-68.
Biochemical Classification of Disease-associated Mutants of RAS-like Protein Expressed in Many Tissues (RIT1).J. Biol. Chem. 2016-07-22;291(30):15641-52.
Follow IRIC: