Publications

Heritable variation in telomere length predicts mortality in Soay sheep.Froy H, Underwood SL, Dorrens J, Seeker LA, Watt K, Wilbourn RV, Pilkington JG, Harrington L, Pemberton JM, Nussey DHProc Natl Acad Sci U S A 2021-04-13;118(15).

A novel p53 regulator, C16ORF72/TAPR1, buffers against telomerase inhibition.Benslimane Y, Sánchez-Osuna M, Coulombe-Huntington J, Bertomeu T, Henry D, Huard C, Bonneil E, Thibault P, Tyers M, Harrington LAging Cell 2021-03-04:e13331.

Catechin from Burkea africana Hook. Exhibits in vitro inhibition of human telomerase activity.Eboji OK, Borges G, Harrington L, Lin W, Sofidiya MO, Sowemimo AANat Prod Res 2020-10-14:1-5.

Re-equilibration of imbalanced NAD metabolism ameliorates the impact of telomere dysfunction.Sun C, Wang K, Stock AJ, Gong Y, Demarest TG, Yang B, Giri N, Harrington L, Alter BP, Savage SA, Bohr VA, Liu YEMBO J 2020-09-16:e103420.

Genome-Wide Screens Reveal that Resveratrol Induces Replicative Stress in Human Cells.Benslimane Y, Bertomeu T, Coulombe-Huntington J, McQuaid M, Sánchez-Osuna M, Papadopoli D, Avizonis D, Russo MST, Huard C, Topisirovic I, Wurtele H, Tyers M, Harrington LMol Cell 2020-09-03;79(5):846-856.e8.

Telomere dysfunction cooperates with epigenetic alterations to impair murine embryonic stem cell fate commitment.Criqui M, Qamra A, Chu TW, Sharma M, Tsao J, Henry DA, Barsyte-Lovejoy D, Arrowsmith CH, Winegarden N, Lupien M, Harrington LElife 2020-04-16;9.

Qualitative Changes in Cortical Thymic Epithelial Cells Drive Postpartum Thymic Regeneration.Dumont-Lagacé M, Daouda T, Depoërs L, Zumer J, Benslimane Y, Brochu S, Harrington L, Lemieux S, Perreault CFront Immunol 2020-02-11;10:3118.

Editorial overview: The instability of the cancer genome: it starts at the end.Harrington L, Baird DMCurr. Opin. Genet. Dev. 2020-02-01;60:iii-vi.

Petite Integration Factor 1 (PIF1) helicase deficiency increases weight gain in Western diet-fed female mice without increased inflammatory markers or decreased glucose clearance.Belmonte FR, Dedousis N, Sipula I, Desai NA, Singhi AD, Chu Y, Zhang Y, Bannwarth S, Paquis-Flucklinger V, Harrington L, Shiva S, Jurczak MJ, O'Doherty RM, Kaufman BAPLoS ONE 2019-05-28;14(5):e0203101.

Understanding diversity in telomere dynamics.Monaghan P, Eisenberg DTA, Harrington L, Nussey DPhilos. Trans. R. Soc. Lond., B, Biol. Sci. 2018-03-05;373(1741).

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