Publications

HLF Expression Defines the Human Hematopoietic Stem Cell State.Lehnertz B, Chagraoui J, MacRae T, Tomellini E, Corneau S, Mayotte N, Boivin I, Durand A, Gracias D, Sauvageau GBlood 2021-09-09.

A genetic screen in Drosophila uncovers the multifaceted properties of the NUP98-HOXA9 oncogene.Gavory G, Baril C, Laberge G, Bidla G, Koonpaew S, Sonea T, Sauvageau G, Therrien MPLoS Genet 2021-08-12;17(8):e1009730.

Overexpression of CD200 is a Stem Cell-Specific Mechanism of Immune Evasion in AML.Herbrich S, Baran N, Cai T, Weng C, Aitken MJL, Post SM, Henderson J, Shi C, Richard-Carpentier G, Sauvageau G, Baggerly K, Al-Atrash G, Davis RE, Daver N, Zha D, Konopleva MJ Immunother Cancer 2021-07-01;9(7).

Cut-like homeobox 1 (CUX1) tumor suppressor gene haploinsufficiency induces apoptosis evasion to sustain myeloid leukemia.Supper E, Rudat S, Iyer V, Droop A, Wong K, Spinella JF, Thomas P, Sauvageau G, Adams DJ, Wong CCNat Commun 2021-04-30;12(1):2482.

Atypical acute myeloid leukemia-specific transcripts generate shared and immunogenic MHC class-I-associated epitopes.Ehx G, Larouche JD, Durette C, Laverdure JP, Hesnard L, Vincent K, Hardy MP, Thériault C, Rulleau C, Lanoix J, Bonneil E, Feghaly A, Apavaloaei A, Noronha N, Laumont CM, Delisle JS, Vago L, Hébert J, Sauvageau G, Lemieux S, Thibault P, Perreault CImmunity 2021-04-13;54(4):737-752.e10.

Zinc finger protein E4F1 cooperates with PARP-1 and BRG1 to promote DNA double-strand break repair.Moison C, Chagraoui J, Caron MC, Gagné JP, Coulombe Y, Poirier GG, Masson JY, Sauvageau GProc Natl Acad Sci U S A 2021-03-16;118(11).

UM171 Preserves Epigenetic Marks that Are Reduced in Ex Vivo Culture of Human HSCs via Potentiation of the CLR3-KBTBD4 Complex.Chagraoui J, Girard S, Spinella JF, Simon L, Bonneil E, Mayotte N, MacRae T, Coulombe-Huntington J, Bertomeu T, Moison C, Tomellini E, Thibault P, Tyers M, Marinier A, Sauvageau GCell Stem Cell 2021-01-07;28(1):48-62.e6.

UM171-Expanded Cord Blood Transplants Support Robust T Cell Reconstitution with Low Rates of Severe Infections.Dumont-Lagacé M, Li Q, Tanguay M, Chagraoui J, Kientega T, Cardin GB, Brasey A, Trofimov A, Carli C, Ahmad I, Bambace NM, Bernard L, Kiss TL, Roy J, Roy DC, Lemieux S, Perreault C, Rodier F, Dufresne SF, Busque L, Lachance S, Sauvageau G, Cohen S, Delisle JSTransplant Cell Ther 2021-01-01;27(1):76.e1-76.e9.

Single UM171-expanded cord blood transplant can cure severe idiopathic aplastic anemia in absence of suitable donors.Claveau JS, Cohen S, Ahmad I, Delisle JS, Kiss T, Lachance S, Sauvageau G, Busque L, Brito RM, Bambace N, Bernard L, Roy DC, Roy JEur J Haematol 2020-12-01;105(6):808-811.

Newly diagnosed multiple myeloma patients treated with tandem auto-allogeneic stem cell transplant have better overall survival with similar outcomes at time of relapse compared to patients who received autologous transplant only.LeBlanc R, Claveau JS, Ahmad I, Delisle JS, Bambace N, Bernard L, Cohen S, Kiss T, Lachance S, Landais S, Roy DC, Sauvageau G, Roy JClin Transplant 2020-09-27:e14099.

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