New oral protease-activated receptor 4 antagonist BMS-986120: tolerability, pharmacokinetics, pharmacodynamics, and gene variant effects in humans.Merali S et al.Platelets 2022. > Plus

Structure-based discovery of nonopioid analgesics acting through the α_2A-adrenergic receptor.Fink EA et al.Science 2022. > Plus

From a Cone Snail Toxin to a Competitive MC4R Antagonist.Reynaud S et al.J Med Chem 2022. > Plus